Sofia Jupither debuted as director in 2001 with Jon Fosse's Visits at Helsingborgs Stadsteater. Her following plays included The Girl on the Sofa performed at Stockholms Stadsteater in 2002 and To Damascus performed at Strindbergs Intima Teater in 2003. In 2005, Sofia debuted as a director in Norway with the world premiere of Jon Fosse's Sleep at the National Theatre in Oslo, a performance that was recorded by Norwegian TV and that has been Fosse’s most watched play.
Since then, Sofia has directed a number of acclaimed performances on stages in Sweden as well as in Norway, including The Wild Duck at Rogaland Teater in Stavanger, The Glass Menagerie and The Seagull at The National Theatre in Oslo, her own adaptation of A Dream Play on the National Theatre's Torshovs stage, Who's Afraid of Virginia Woolf?, Ghosts and Playing With Fire at Stockholms Stadsteater, as well as Ibsen's A Doll's House and In the Summer House by Jane Bowles at the Royal Dramatic Theatre, Dramaten. Since 2009, Sofia Jupither is an artist-in-residence at the Folkteatern, where she directed Lars Norén's play, Skalv, in the fall of 2010, and Jon Fosse's play, Winter, in the spring of 2012. She then worked with the set designer, Erlend Birkeland, on Fragmente, which is the eleventh production they are working on together.
Since her production for Villes en scène / Cities on stage, she directed 3.31.93 by Lars Norén at the Stockholm city theatre and made her debut as an opera-director with Salome by Strauss at the Royal Opera in Stockholm with the Swedish soprano Nina Stemme in the title-role.
Production Folkteatern Göteborg and Théâtre National/Bruxelles.